This term is taken from, (Jack Van Impe) King James Bible, page 75:
(Genesis 3:15) "referring to some progeny of Eve that would be at enmity with the seed of the serpent, the devil (Isaiah 7:14; Galatians 4:4). Ultimately and Specifically, this person is Jesus Christ. Generally, it is true that the serpent's seed has always been at war with the womans seed. It still continues today."
~ JVI King James Bible